ObjectiveTo examine the effects of apalutamide on endocrine function and flare prevention in metastatic hormone-sensitive prostate cancer (mHSPC) patients administered GnRH agonists. MethodsThe first newly diagnosed mHSPC patient took apalutamide for 2 weeks followed by combination with GnRH agonist. as recommended by clinical guidelines. Serum luteinizing hormone (LH). https://www.houseandholders.shop/product-category/collections/